ThehnRNP(heterogeneousnuclearribonucleoprotein)familyisagroupofRNA-bindingproteinsthatplaycrucialrolesinvariousaspectsofRNAmetabolism,includingsplicing,transport,stability,andtranslation.Theseproteinsareessentialformaintainingcellularhomeostasisandhavebeenimplicatedinnumerousphysiologicalandpathologicalprocesses.Recentresearchhasshedlightontheirdiversefunctionsinhealth,aswellastheirinvolvementindiseasessuchascancer,neurodegenerativedisorders,andviralinfections.UnderstandingthemolecularmechanismsofhnRNPsofferspotentialtherapeutictargetsfortreatingtheseconditions.ThisreviewexploresthecurrentknowledgeofthehnRNPfamily,highlightingtheirbiologicalsignificanceandtheirimpactonhumanhealthanddisease.
