Prothioconazoleisawidelyusedtriazolefungicideeffectiveagainstvariousfungaldiseasesinwheat.However,itsmetabolite,prothioconazole-desthio,mayposepotentialriskstohumanhealthandtheenvironment.Thisstudyfocusesonevaluatingtheresiduelevelsofprothioconazoleanditsmetaboliteinwheatfields,aswellasassessingtheassociateddietaryintakerisks.Byanalyzingfieldtrialdataandapplyingriskassessmentmodels,theresearchaimstoprovidescientificinsightsintothesafeuseofprothioconazoleinagriculturalpractices,ensuringcompliancewithfoodsafetystandardsandminimizingpotentialhealthhazards.Thefindingswillcontributetoregulatorydecision-makingandpromotesustainablepesticidemanagementinwheatproduction.