Celladhesionmolecules(CAMs)playacrucialroleinmyogenesis,theprocessofmuscleformationandregeneration.Duringmyogenesis,CAMsmediatecell-cellandcell-matrixinteractions,facilitatingmyoblastproliferation,migration,differentiation,andfusionintomultinucleatedmyotubes.KeyCAMsinvolvedinthisprocessincludecadherins,integrins,andimmunoglobulinsuperfamilymemberslikeNCAM.Thesemoleculesregulatesignalingpathwaysthatcoordinatecytoskeletalreorganizationandgeneexpressionchangesnecessaryformuscledevelopment.DysregulationofCAMscanleadtoimpairedmuscleformationordisease.UnderstandingCAMfunctionsinmyogenesisprovidesinsightsforregenerativemedicineapproachestargetingmusculardisorders.
